There's a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to minimize afferent ache transmission and make analgesia. Therefore, drugs like clonidine that concentrate on alpha-2 receptors can impact the transmission of agony. For people who get dizzy when standing: https://thomasw095dyr1.wikitron.com/user