Butabarbital improves toxicity of methoxyflurane by increasing metabolism. Contraindicated. Greater metabolism of methoxyflurane to nephrotoxic compounds. butabarbital will lower the extent or impact of midazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. butabarbital will lessen the level or outcome of hydrocortisone by impacting hepatic/intestinal... https://tomj752ihi2.blog4youth.com/profile